In vitro methods cannot capture all complexities in the body that occur during in vivo tests. Nevertheless, they are an indispensable part of the evaluation process of product effects on the skin. The various in vitro measurement methods are on the rise and will become increasingly important in the future, as Courage + Khazaka explains
The importance of in vitro tests for analysing the skin and its functions has increased continuously in recent years. Cultured skin models and skin-like tissue mimicking the characteristics and functions of human skin are readily available and provide a controlled basis for numerous analyses, allowing researchers to manipulate variables more precisely.
Notwithstanding the complex interactions between a living body and the environment, they also offer the advantage that tests will score rather reproducible results. This enables the study of specific factors such as environmental influences or genetics on the skin. In particular for cosmetic and dermatological research, in vitro tests offer many advantages.
Not only do in vitro measurements provide precise insights into the dermal absorption of substances, crucial for assessing the safety of cosmetics, pharmaceuticals and other products. Time and financial aspects also play an important role: in vitro tests offer a cost-efficient and time-saving alternative to costly in vivo studies.
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