Skin barrier function, principally the stratum corneum, is the primary line of defence against extrinsic stress such as UV-induced photo-damage, insults from microbial infections and physical deterioration resulting from ageing and environmental exposure.
Scientific evidence suggests that both intrinsic and environmental factors contribute to ‘compromised’ skin barrier function. The stratum corneum functions as an effective barrier and is critical for controlling and preventing water loss. The physiological effect of optimum barrier function allows skin to recover and repair damaged cells through an ongoing regenerative process. Since skin is the body’s first line of defence against any physical or chemical assault, strengthening barrier function is the primary means to improve compromised skin. Barrier protection restores skin hydration and overall health, reducing the appearance of signs of premature ageing.
Premature ageing and compromised skin
When unchecked, compromised barrier results in deteriorating skin function and could ultimately lead to premature ageing.1 Figure 1 summarises the various factors that compromise skin and highlights the effects they have on skin barrier function. Chronic premature ageing is the result of a decreased barrier function that eventually leads to internal skin damage. Compromised skin results when the epidermis is damaged and can no longer protect itself or hold on to moisture.
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