New studies performed in 2013 on Venuceane, Sederma’s anti-ageing active that offers ultraviolet (UV) protection, demonstrate it to be also highly efficient against infrared (IR)-ageing. Both UV and IR induce skin damage but in different ways.
An efficient IR protection requires specialised strategies that involve an adaptive response to increased heat (specific to IR radiation) and the counteraction of IR-induced ROS production. Venuceane has successfully been demonstrated to do just this. The ingredient improves hydration via the protection of the mitochondrial integrity known to be particularly damaged by IR radiation (ATP synthesis and mitochondrial water content increased by 79%). It also lessens the inflammatory conditions (PGE2: –54%, IL-6: –53%, IL-8: –61%, vs. IR-irradiated control), and prevents the denaturation of matrix macromolecules in order to limit wrinkle formation (collagen I: +70%, fibrillin-I: +28% vs. IR-irradiated control). Venuceane is an anti-ageing active that meets expectations for a new generation of photoprotection based on UV and IR protection. Derived by biotechnology, Venuceane, is a ferment that is rich in multifunctional and stable enzymes. In addition, it also complies with Chinese regulations for cosmetics ingredients.
