Discovering Alteromonas lipotrueae for expression lines

LipoTrue presents the first vertically integrated active ingredient in cosmetics, from strain identification to the development and delivery of a novel marine ferment targeting neuron-muscle communication holistically.

V/WA™ is a fully vertically integrated product, completely controlling the three steps of the process: D/scover, Develop and Del/ver. V/WA™ is the active ingredient obtained from the fermentation of a newly identified Alteromonas species: Alteromonas lipotrueae.

Alteromonas lipotrueae was found living in symbiosis on the surface of the Mediterranean Sea’s most stinging jellyfish, the Pelagia noctiluca. The metabolomic analysis of the ferment from this microorganism confirmed that it contains biomimetic compounds linked to muscle contraction.

V/WA™ relaxes expression wrinkles acting along the three steps of neuromuscular communication: neuritogenesis & neuronal migration, synaptic vesicles recycling and muscle contraction. V/WA™ smoothed wrinkles on crow’s feet, the forehead and even those challenging hidden wrinkles that are revealed to the world when smiling or frowning.

Two panels of 20 women aged 45-60 with expression lines in crow’s feet and forehead/frown applied either a cream with 3% marine ferment or a placebo to their entire face twice daily for 28 days. Wrinkle depth and volume in the crow’s feet and forehead/frown area were evaluated by fringe projection during frowning, smiling, and neutral expressions to assess the ferment's potential in reducing hidden wrinkles. 

In just 10 minutes, the cream with the marine ferment notably reduced crow’s feet wrinkles by 9% in volume and depth. Similarly, volunteers experienced an average 7% decrease in volume and 8% in depth in 10 minutes also when smiling. After 28 days, the marine ferment further smoothed wrinkle depth by up to 35% (neutral and smiling) and volume by up to 26% (neutral) and 35% (smiling). 

The marine ferment was tested to see if it could lessen the increase of wrinkles caused by smiling. In ten minutes, it reduced this rise by 13% in depth and 11% in volume.

From the discovery of a new microorganism, through the development of a new active ingredient to the delivery of a novel approach for expression wrinkles.

 

URL: https://lipotrue.com/products/viwa/

To learn more about V/WA™ visit www.lipotrue.com or contact us at info@lipotrue.com

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