Chemyunion presents an in vitro study showing the action of a resurrection plant and green coffee active in reducing lipofuscin induced by ultraviolet radiation in human fibroblasts, acting as a detoxifying and protective agent. As a result of these differential mechanisms, the clinical study underscores the potential of the resurrection plant and green coffee active formulation in delivering remarkable skin brightening and pro-ageing effects
The face and hands serve as the canvas of our age, revealing the first brushstrokes of the passage of time. The emergence of telltale signs such as wrinkles, sagging, dryness, age spots, freckles, and discoloration signifies the intricate dance between ageing and skin health.
This article delves into the fascinating world of age spots, with a particular focus on their formation, exploring the interplay between melanin, lipofuscin, and the essential cellular processes of autophagy and proteasome activity.
Age spots manifest as light brown to black pigmented lesions, varying in size from millimetres to small centimetres. Typically appearing on sun-exposed skin, these spots are not solely a result of melanin accumulation but also involve the presence of 'cellular waste' or lipofuscin.1,2
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