Ichimaru Pharcos introduced ’Izayoi’ as a UV care active and ‘Glycerin Natural Active Line’ at in-cosmetics Global 2017.
Firstly, the UV Care natural active ingredient called Izayoi has very unique biological pathway to prevent sunburn and photo-ageing by a newly revealed anti-inflammation pathway. Consumers get the benefit of anti-ageing to prevent sunburn, wrinkles and age spots/pigmentation. This item is recommended for sunscreens and skin care for people who become more sensitive to UV with their ageing.
According to Ichimaru Pharcos’s studies for MED (Minimum Erythema Dose) on the same people over 10 years, MED for the same people becomes lower with ageing, which means aged skin is more sensitive to UV. Ichimaru Pharcos found one of the reasons was that aged keratinocyte are more damaged by UVB compared to young keratinocyte.
Keratinocyte damaged by UVB release denatured U1RNA which is one of the DAMPs (Damage-associated molecular patterns), and the surrounding non-damaged keratinocyte recognises the DAMPs to initiate an inflammatory reaction leading to skin ageing like wrinkles, age spots or pigmentation. DAMPs influence is getting higher on aged keratinocyte, so older people need to pay attention to more sun care.
Izayoi inhibits DAMPs response on keratinocyte at the earliest stage of inflammation caused by UVB, so it is the most significant way to prevent photo-ageing. Izayoi inhibits inflammation cytokines induced by a DAMPs-like substance on human keratinocyte but other conventional anti-inflammation agents do not have the same function. On human clinical studies, Izayoi inhibited facial erythema caused by the sun exposure.
In addition, this year Ichimaru Pharcos will introduce some new additional data conducted by a world famous dermatologist. The primary objectives are if Izayoi has inhibition of sun induced erythema and photo dermatitis, sun protection, improvement in skin tone/ anti- tanning effect, reduction of spots and pigmentation, improvement of evenness of skin tone by dermatological examination. The secondary objectives are improvement in fine lines and wrinkles, improvement in skin elasticity, improvement in skin hydration or moisturising level.
Izayoi is a natural plant extract made from rose fruit called “Shiri”, of Chinese Medicine. The fruit is rich in VC, so it is also used for dietary supplements and fruit liquor. Izayoi uniquely inhibits the DAMPs related inflammation induced by UVB while other common anti-inflammation agents do not; therefore, Izayoi gives the cosmetic industry a new era of sun care.
Secondly, due to demand on actives in natural solvent, Ichimaru Pharcos developed ‘Glycerin Natural Active Line’ coming up with several popular actives. All items here are composed of a plant extract and Glycerin which is the most welcomed carrier in the world. Izayoi G is UV care, Ougon Liquid G is anti-pollution, Taisoh Liquid G is slimming, Biobenefity G is pore care, PrincessCare G is anti-wrinkle, Neem Leaf Liquid G is anti-inflammation, ecofarm Bilberry Leaf-G is anti-stress and anti-blue light, and ecofarm Cucumber-G is moisturising active. ecofarm series are organic ingredients certified by Ecocert. Of course, all of them are paraben free.
