In October the Japanese biologist Yoshinori Ohsumi was awarded the 2016 Nobel Prize in Physiology or Medicine for having elucidated the biological mechanism of autophagy.
It is a powerful process for degrading and recycling the constituents of cells. His work showed the importance of autophagy dysfunctions in a number of pathologies, as well as in the ageing process.
As recently as 2006, autophagy was only ‘backgroundnoise’ in dermatology. Since that date, Silab’s advanced research with its university partners has enabled it to implement a research strategy to more fully understand this machinery and its functions in the skin.
Silab has unique experience with cutaneous autophagy resulting from its work with novel biological models. This essential modelling approach is a major strength in the investigation of the mechanisms of autophagy.
In 2009, Silab proposed the cosmetic ingredient Celldetox, a modulator of autophagy, currently available on the market. This biotechnology ingredient acts on autophagy markers (lysosomes, LC3), revives the radiance of intoxicated skin and smoothes microrelief after only 2 weeks of use; after 4 weeks, the complexion is uniform and wrinkles are attenuated. It is a genuine booster of cell detoxification and longevity, providing a second youth to fatigued skin.
