Bioactive fucoidan fractions as cosmetic ingredients

Marinova, an Australian biotechnology company, developed two speciality cosmetic ingredients from marine algae. Maritech Bright is a Fucus vesiculosus derived extract (pictured) comprising both fucoidan and polyphloroglucinol, and Maritech Reverse is a high purity fucoidan from Undaria pinnatifida. Fucoidan is a sulphated, fucose rich polysaccharide with multiple bioactivities. Polyphloroglucinols are unique marine algal derived polyphenols with profound antioxidant activity.

In clinical trials, the protective and soothing activity of 0.3% w/v preparations of each of the Maritech products was assessed. Both products were clinically proven to be highly effective at protection and soothing as measured by erythema and transepithelial water loss after solar stimulation. Maritech Reverse was assessed for elasticity and wrinkle depth in older Caucasian women, and demonstrated an increase in elasticity and decrease in wrinkle depth, roughness and redness. Clinical studies on wrinkles and lightening will be discussed.

In vitro tests demonstrate potent antioxidant, antibacterial and anti-ageing properties of these unique extracts. Together, these properties place Maritech Bright and Maritech Reverse as highly effective clinically proven speciality ingredients.

Marine macroalgae or ‘seaweeds’ are recognised in the cosmetic world as ‘spa treatment ingredients’. They contain a variety of extractable polysaccharides, some of which are known commercial food ingredients. These include gelling polysaccharides such as carrageenans (from red macroalgae) and alginates (from brown macroalgae). Fucoidans are a class of non-gelling, sulphated polysaccharides found only in brown macroalgae and echinoderms.1,2 Their sugar backbone composition, structure and sulphation patterns differ according to their origin and the extraction techniques used. The common feature is a high content of the backbone sugar ‘fucose’. The well known Japanese seaweed ‘wakame’ (Undaria pinnatifida) yields a fucoidan with a high ratio of the sugar ‘galactose’ and is acetylated. The northern hemisphere ‘bladderwrack’ (Fucus vesiculosus) yields a fucoidan with a very high fucose content, which is not acetylated. Both fucoidans are of high molecular weight, highly branched, and heterodisperse.

Log in or register FREE to read the rest

This story is Premium Content and is only available to registered users. Please log in at the top of the page to view the full text. If you don't already have an account, please register with us completely free of charge.

Latest Issues

Society of Cosmetic Chemists 78th Annual Scientific Meeting & Showcase

JW Marriot Los Angeles L.A. LIVE
11th - 13th December 2024

PCHi 2025

China Import and Export Fair Complex Guangzhou
19-21 February 2025