Autophagy, which was recently discovered in skin, stands out today as a powerful mechanism; essential for detoxifying cells and guaranteeing their proper functioning, thereby limiting the senescence.
Based on the autophagic pathway, Celldetox® (INCI Name: Yeast Extract) detoxifies cells and increases cell longevity by removing altered components that saturate it. Its efficacy was demonstrated in vitro and in vivo.
Cells have their own protection system in order to maintain their homeostasis. They have powerful proteolytic machinery composed of two major mechanisms which complement each other in the elimination and detoxification of altered proteins and/or organelles: proteasome and the autophagic pathway.
The principal function of the proteasome is targeted degradation of short-lived soluble proteins, both functional (small regulatory proteins) and non-functional (misfolded proteins).
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