Silab has taken the wraps off Senevisium, a natural anti-ageing ingredient made from Ginkgo biloba.
The French cosmetic actives producer says the ingredient is capable of reactivating the natural elimination of senescent fibroblasts by the immune system.
Senevisium acts transversally on the dermis and the epidermis for an anti-wrinkle action and a rapid radiance-boosting effect, it adds.
Senescence, a central factor of ageing, is controlled by the immune system that effectively locates and eradicates senescent cells that are harmful to the cutaneous environment.
Over time, however, some senescent fibroblasts implement immunoevasion strategies to avoid being eliminated.
Thanks to novel in vitro and in vivo modelling studies, Silab revealed the accentuation of the immunoevasion mechanism at the level of the skin after the age of 60, inducing profound changes (wrinkles, dull complexion, loss of elasticity and senescence spots).
Through its targeted action, Senevisium is able to restore the natural elimination of immunoevasive senescent fibroblasts by the immune system by circumventing their two immoevasion pathways.
By allowing deleterious immunoevasive senescent fibroblasts to be recognized again and eliminated, Senevisium protects the skin from their harmful effects on matrix synthesis and epidermal renewal.
Tested at 2% in Caucasian volunteers, Senevisium enables the skin to restore its density and elasticity. The stage of wrinkles is reduced and complexion radiance is enhanced.
The volunteers themselves confirm these results since 100% of them find their skin firmer, and their complexion lighter and more uniform after 28 days of treatment.
Silab was inspired by the extraordinary capacity of Ginkgo biloba to withstand the test of time and by the powerful immune system of this supercentenarian tree with a unique anti-aging biological heritage.
Its leaves were then beneficially used to restore the capacity of the immune system of mature skin to eliminate senescent cells.
Two French farms (Champagne and Ardèche regions) of Ginkgo biloba, certified organic and biodiversity-friendly, were selected for the supply of green leaves.
Senevisium is a patented active ingredient recommended in all care products for mature skin at the amount of 0.5 to 2.0%.
Available in aqueous solution, it is easy to formulate. It complies with biodiversity regulations and has a natural origin content of 98.8% (ISO 16128). It meets international cosmetic regulations requirements (Europe, United States, China, Japan, etc.).