DSM active counters AGEs
DSM has carried out in vitro studies that found its Alpaflor Edelweiss CB organic plant extract counters the negative effects of advanced glycation end products
DSM has carried out in vitro studies that found its Alpaflor Edelweiss CB organic plant extract counters the negative effects of advanced glycation end products (AGEs), as well as its known ability to protect against ROS-associated signs of skin ageing through its free radical scavenging properties.
The studies showed that the extract decreased AGE formation by 55%; inhibited collagen Type IV glycation by 67%; and increased the activity of glyoxalase-1 (Glo-1) by 65%. Glo-1 plays a key role in protecting keratinocyte proteins against oxidative damage during skin ageing. Further studies, DSM said, showed it to reverse the glycation process by 47% and boost collagen I and IV expression by 111% and 171% respectively.
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