Greying of hair is an unavoidable phenomenon, however, there is a strong consumer expectation to avoid it with natural solutions. Faced with this observation, Silab developed Agreynist, a natural active ingredient capable of regulating the biological pathways leading to greying.
In particular: it restores the oxidative balance of hair, a necessary factor of any anti-greying strategy, not only by reducing the formation of free radicals, but also by activating cell detoxification induced by autophagy; it favours repigmentation of the hair fibre by stimulating the synthesis of melanin with its cytoprotective effect; it re-establishes the structural quality of hair (result from an original modeling study).
Using Raman microspectroscopy, Silab conducted a more detailed analysis of the course of greying and, in a novel way, has shown that there are changes in molecular markers related to biomechanical properties (conformation of proteins) and to the barrier function (organisation of lipids) in grey hair.
In order to address effectively the issue of hair greying, Silab implemented a screening of natural raw materials targeting the indispensable anti-free radical and pro-pigmenting effects. This work led to the identification of two raw materials: black oat seeds (anti-oxidant and detoxifying) and spiny restharrow roots (pro-pigmenting). The use of green solvents combined with enzymatic bioengineering enabled the optimized extraction of molecules of interest. Silab thus concentrated and stabilised in Agreynist the complementary efficacies of these two raw materials obtained from a controlled supply chain. With its protective, detoxifying and repigmenting action, Agreynist (INCI name: Butylene Glycol & Water & Ononis spinosa Root Extract & Avena strigosa Seed Extract) offers a natural solution for grey hair care. Composed of biopeptides and polyphenols, this patented active is available in aqueous solution (recommended amount: 0.5 to 2.5%) and compliant with international cosmetic regulations (Europe, United States, Japan, China, etc.).
