Actives fight exposome induced oxidative stress

Half of the worldwide population lives in cities and is exposed daily to urban pollution. Consequently, pollution has become a public health crisis. By 2030, the urban population will reach 60% and up to 70% by 2050.

The high levels of air pollutants are not limited to China or India anymore as Western capitals like Paris and London often exceed the World Health Organization alert levels. Indeed, it is 90% of those citizens that are exposed to higher levels of air pollutant; particles PM10 & 2,5; than the World Health Organization limits.1 A growing number of scientific and epidemiological studies have demonstrated that human exposure to environmental stress is associated with premature skin ageing and hyper pigmentation.2 The deleterious effect of this stress might be amplified with each other, when combined they form the prooxidant smog also qualified as ‘exposome’.3 The first epidemiological study was conducted on elderly Caucasian women, and showed that exposure to traffic related Particulate Matter (PM2.5-PM10) contributes to skin ageing.2 More studies were performed to provide further evidence that pollution can accelerate skin ageing.4, 5, 6 Not only wrinkle formation but also pigmentation spots appearance could be linked with pollution exposure.2 While the underlying mechanism of action of pollution in skin is not clearly defined, there is strong evidence implicating the generation of Reactive Oxygen Species (ROS) and subsequent state of oxidative stress in all layers of the skin. 5,7,8,9,10,11,12 According to those discoveries, it seems that protecting skin from exposome-induced oxidative stress is the best way to delay skin ageing. 

Deep oceans are hostile environments; cold, dark and poorly oxygenated. However, many living organisms evolved to live under these conditions, developing special abilities that have allowed them to survive. Strombine, a rare amino-acid found in many organisms such as sponges, sand worms, oysters, gastropods seemed to play an essential role in cases of environmental stress. In marine invertebrate such as mussels, Mytilus edulis, strombine accumulation was identified as a metabolic stress marker.13 Data suggest that a high concentration of strombine contributes to regulating osmotic pressure in tissues.14 A newly developed strombine derivative compound will act at a cellular level to prevent and repair the harmful effects of stress. 

Moringa extract the pollution shield

Log in or register FREE to read the rest

This story is Premium Content and is only available to registered users. Please log in at the top of the page to view the full text. If you don't already have an account, please register with us completely free of charge.

Latest Issues

Society of Cosmetic Chemists 78th Annual Scientific Meeting & Showcase

JW Marriot Los Angeles L.A. LIVE
11th - 13th December 2024

PCHi 2025

China Import and Export Fair Complex Guangzhou
19-21 February 2025