The skin, as the protective barrier that separates and isolates the inner from the outer environment, suffers the consequences of the intrinsic factors of ageing (oxidative stress, glycation, inflammation etc), as well as those produced by the so-called extrinsic factors (ionizing radiation, UV-B, pollution, tobacco, eating style etc) all of which may alter its condition and function.
As a consequence, skin may undergo changes leading to photoageing, inflammation, immune dysfunction, imbalance in epidermal homeostasis and other disorders. Recent studies on the field of epigenetics show that the skin undergoes a series of damages that end up accumulating with time and undermine the proper functioning of cells. Our genes lose the ability to meet the necessities and therefore they become ineffective in repairing the damage when and where is needed.
It is well known that from the age of 40, the skin starts losing its density and firmness: production of collagen, elastic fibres and filler substances that lend volume to the skin are drastically reduced, proinflammatory processes increase and cells do not work properly.
Epigenetics
Log in or register FREE to read the rest
This story is Premium Content and is only available to registered users. Please log in at the top of the page to view the full text.
If you don't already have an account, please register with us completely free of charge.
