The lipid composition of human skin is essential for its function. However, the simultaneous quantification of a wide range of stratum corneum and sebaceous lipids is not trivial.
We developed and validated a quantitative high-throughput shotgun mass spectrometry-based platform for lipid analysis of tape-stripped skin samples. Lipotype analyses also other types of skin samples, from monolayers to 3D models. It is now easy to investigate how the healthy skin lipidome is composed, how it changes in diseases or upon intervention with a drug or a cosmetic product. This lipidomic data can be used for cosmetic claim support, topical drug development and personalised cosmetics. More details about this method and its application can be found in: Sadowski T. et al. ‘Large-scale human skin lipidomics by quantitative, high-throughput shotgun mass spectrometry’ Scientific Reports 2017, doi: 10.1038/srep43761
Ultra-broad coverage
Lipotype Shotgun Skin Lipidomics provides a broad coverage of stratum corneum and sebaceous lipids.
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