Environmental factors such as UV radiation or pollution contribute to the production of highly reactive molecules involved in extrinsic skin ageing. The increase of these free radicals in cells enhances oxidative stress leading to protein oxidation.
The Ubiquitin Proteasome System (UPS) is one of the different cellular mechanisms to avoid damaged protein build-up in the cells by degrading them to peptides.
Nevertheless, with age the detoxifying performance of the skin diminishes and, therefore, cutaneous quality is compromised. ScelleyeTM contains plant-insulin-like growth factor 1 (plant-IGF-1), a detoxifying protein able to reactivate, redensify and protect eye skin contour covering multiple concerns such as dark circles and crow’s feet under the tested conditions.
The eye skin contour is extremely fragile and is constantly exposed to environmental aggressions such as radiation (UV, IR, blue light) and pollutants. It is ten times thinner than facial skin, and thus it is more prone to suffer damage as a result of the action of free radicals and other aggressors, both produced by internal and external factors. The final result is the appearance of wrinkles and undesired pigmentation due to alteration in melanin, haemoglobin and iron levels.
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