Multi-targeted complex offers range of benefits

The concept of multi-targeting is generally used for the treatment of various diseases by the pharmaceutical industry. One living cell needs a wide range of materials for it to function properly, and cells contain many channels that influence its behaviour.

In each channel, there are different positions for the various molecules docking with them. For example, molecule M1 may enter into it and dock with the targets inside the channel. By docking to the receptors, the channel may lose its function. This logically will affect the living cell. If this channel is the most important one, the strong docking state of molecule M1 may lead to cell death. 

If the docking of M1 to the target is not strong enough, this molecule cannot kill the cell via this channel. However, this channel may have some different important targets for molecules, like M2 and M3 docking. In this way, three molecules M1 to M3 would form more powerful docking states, and lead to cell death. Thus, multi-target complex (ingredients) may have higher efficiency than single target ingredients

In general a single compound may be the most efficient method to treat some illnesses. For example, penicillin is a widely used antibiotic, and it has been used to save hundreds of thousands of people’s  lives.

Log in or register FREE to read the rest

This story is Premium Content and is only available to registered users. Please log in at the top of the page to view the full text. If you don't already have an account, please register with us completely free of charge.

Latest Issues

Society of Cosmetic Chemists 78th Annual Scientific Meeting & Showcase

JW Marriot Los Angeles L.A. LIVE
11th - 13th December 2024

PCHi 2025

China Import and Export Fair Complex Guangzhou
19-21 February 2025