Alain Thibodeau, PhD - Atrium Biotechnologies, Canada
UV irradiation has been shown to have several effects on skin: DNA lesions; cellular apoptosis; immunosuppression and inflammation/erythema. With respect to actinic skin ageing - or photo-damage - the increase in matrix metalloproteinase (MMP) activation and expression is the most recognised degradation pathway induced as a result of UV exposure.
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