One of the results of ageing is that the communication process between skin cells, which is mediated by growth factors, is reduced. As a consequence, the activity of fibroblasts decreases. Unfortunately, this strongly affects the extracellular matrix (ECM), the structural network of the skin. The result of this is a reduction in the skin’s firmness, elasticity and density.
The reduced synthesis of natural growth factors affects the structural network of the skin
Without question, it is a challenge to reach dermal fibroblasts by topically-applied cosmetics. However, as these cells communicate with the keratinocytes, which are in the outer skin layers, they can be targeted by this exact communication process. This dialogue, which is crucial for a youthful appearance, is in turn mediated by growth factors that are impaired with age.
Reaching fibroblasts via intercellular communication
DermCom, from Mibelle, uses this smart strategy to successfully rejuvenate the skin matrix deep in the dermis. It stimulates the communication between epidermal and dermal skin cells by triggering keratinocytes to secrete growth factors. These growth factors enhance the synthesis of collagen and elastin in the dermis.
Clinical studies have confirmed that DermCom both improves and repairs skin texture through its growth-factor like activity. The studies have shown that it:
•Boosts collagen and elastin production.
•Stimulates natural growth factors of the skin.
•Renews the skin’s resilience and firmness.
DermCom is based on the bulbs of Crocus chrysanthus. Also known as ‘Cream Beauty’, this flower is a universal symbol of rejuvenation and youthfulness.
Double silver award winner at in-cosmetics:
• Innovation Zone Best Ingredient Award 2012
• BSB Innovation Prize 2012
