Greentech demonstrate that an active made from an extract of Schisandra chinensis berries can greatly improve cell longevity by slowing down the effects of time and preventing the appearance of wrinkles
Over the centuries, human life expectancy has increased considerably, mainly as a result of medical progress, technological advances and improved living conditions. This increase in life expectancy highlighted certain regions known as 'blue zones',1 where people live exceptionally long and healthy. These areas, such as Okinawa in Japan, Sardinia in Italy and Ikaria in Greece, have become subjects of study for understanding the factors that contribute to human longevity.
Besides lifestyle characteristics that promote longevity, such as regular physical activity, predominantly plant-based diet, moderate alcohol consumption, stress reduction, the individual genome plays a role in slowing down physiological changes, since certain genes, known as longevity genes, tend to be over-expressed in centenarian populations.2
SIRT6 (sirtuin 6) and FOXO3 (Forkhead box 3) are described as longevity genes.3-6 SIRT6 is involved in regulating longevity and DNA repair,7 as well as controlling inflammation via NFkB (Nuclear factor-kappa B) and oxidative stress via NRF2 (Nuclear Factor, Erythroid 2 Like 2) transcription factors.8,9
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