Sederma has developed Phytosonic, a product designed to combat hypertrophy of adipose tissue by acting on pre-adipocytes and mature adipocytes. Phytosonic has vegetal origin and is derived from the new anti-fat technologies of ultrasound cell lysis.
The product is able to selectively detach hypertrophied adipocytes without destroying them. The properties of Phytosonic enable to target slimming not only at cellular level but also at tissue level, as demonstrated, for the first time, by a three dimensional reconstructed hypodermis model. A clinical study was carried out on 27 female volunteers who applied a cream containing 3% Phytosonic morning and night for 2 months. The results obtained showed the efficacy of the product on stubborn cellulite with a very significant decrease, ranging from 17% to 69% in adipose tissue infiltration into the dermis after 2 months of treatment. The ultrasound measurements demonstrated a very significant decrease in adipose tissue thickness in the thigh and knee. The decreases were 8.5% (up to 18.6%) and 8.2% (up to 20%) respectively. Therefore, it resulted in a mean reduction in thigh circumference of 1 cm and a reduction of up to 2 cm vs the untreated thigh.