DSM has launched a naturally derived grade of vitamin B12 (INCI: Cyanocobalamin). This is produced via non-GMO bacterial fermentation, has a natural origin index of 68.7%, and is both Halal-approved and vegan-compliant.
The new grade is said to relieve sensitive and stressed skin, and to help relieve itchy, irritated, inflamed, red and cracked skin. It also helps to prevent photo-damage and protect the skin barrier damage induced by inflammation, while helping to speed up cell recovery and regeneration and imparting “a pleasant pink colour” to products.
According to tests cited by DSM, this ingredient is active on atopic dermatitis, reducing erythema and pruritus in vivo. It prevents inflammation ex vivo, with strong reductions of inflammasome and inflammatory cytokines, such Il1-ß. At 0.01% concentration, it reduces the over-expression of miR-22-3p by 61%, leading to a reduction of inflammasome ex vivo. Finally, it reduces mast cell degranulation by 31%.
