Sytheon has published a new study highlighting the clinical safety and efficacy of its Synastol TC active ingredient in reversing pollution induced skin damage in Clinical, Cosmetics & Investigative Dermatology
Sytheon has published a new study highlighting the clinical safety and efficacy of its Synastol TC active ingredient in reversing pollution induced skin damage in Clinical, Cosmetics & Investigative Dermatology. This is available for download on the company website.
This study showed that Synastol TC exhibited longer-lasting and more efficient antioxidant neutralization of reactive oxygen species (ROS) than α-tocopherol and safeguarded keratinocytes against increases in intracellular ROS, inflammatory cytokines (IL-6 and IL-8) and peroxidation of membrane lipids following exposure to particulate matter for up to three hours.
An eight-week trial on female subjects who had lived at least five years in Bangalore, a highly polluted city in India, “yielded significant improvements in dermatologist scores and subject self-assessments for skin texture, hydration, tone, firmness, and radiance, compared with its placebo,” the company said. “Indeed, self-perceived improvements by subjects drove compliance over the course of the study.”
Synastol TC is made from the fruit of Terminalia Chebula, an Asian herb that has long been used in traditional medicine for its healing powers. It is produced via a proprietary process that guarantees standardised levels of the bioactive phytochemicals that account for its biological properties, i.e. 70% hydrolysable tannins, including ≥ 20% chebulinic and ≥ 15% chebulagic acids.
