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iPeptide: Improving sleep quality

LipoTrue has shared some new results for its iPeptide, which has also won the 2021 BSB Innovation bronze prize. The company describes iPeptide as “a good sleep biohacking peptide, developed to down-regulate IL-33 expression”

LipoTrue has shared some new results for its iPeptide, which has also won the 2021 BSB Innovation bronze prize. The company describes iPeptide as “a good sleep biohacking peptide, developed to down-regulate IL-33 expression”.

IL-33 is a pro-inflammatory cytokine that is released when cell damage activates the immune response, and induces oxidative stress and further inflammation. It is over-expressed in conditions of chronic inflammation like atopic dermatitis and obstructive sleep apnoea.

In test in vivo, iPeptide was shown to modulate chronic inflammation and the damage induced by hyperglycaemia due to sleep deprivation. It also has a melatonin-like protection effect and reinforces the first line of immune defence.

Insufficient sleep is associated with chronic low-grade inflammation, oxidative stress, impaired immune response, reduced melatonin levels and elevated glucose levels. These all induce more oxidative stress and inflammation, resulting in a tired look, hanging eyelids, dark circles, eyebags and wrinkles.

The company found that, among a panel volunteers who self-assessed their sleep patterns after using a cream containing 3% iPeptide and sleeping for five to six hours per day for 28 days:

· 73% had a feeling of having slept all night

· 83% experienced refreshed skin

· 63% experienced a cooling effect

· 69% enjoyed an anti-fatigue effect

See more about LipoTrue

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Upcoming Events

Cosmetorium

Palau de Congressos, Barcelona, Spain
20 – 21 October

NYSCC Suppliers’ Day 2021

Jacob K. Javits Convention Center, New York
10 - 11 November 2021

SCS Formulate

Coventry Building Society Arena
16 – 17 November

Making Cosmetics

MiCo Milano Congressi, Milan
25 - 26 November

in-cosmetics Global 2022 - Paris

1 Pl. de la Porte de Versailles, Paris
5 - 7 April 2022

in-cosmetics Asia 2022

BITEC Bangkok, Thailand
1 - 3 November 2022

Access the latest issue of Personal Care Magazine on your mobile device together with an archive of back issues.

Download the FREE Personal Care Magazine app from your device's App store

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