Cranberry-based anti-ageing ingredient

Silab has launched its latest anti-ageing active ingredient, Peptilium (Vaccinium macrocarpon (Cranberry) Fruit Extract). This is composed of natural biopeptides purified to 95%. These are obtained by up-cycling cranberry fruit press cake

Silab has launched its latest anti-ageing active ingredient, Peptilium (Vaccinium macrocarpon (Cranberry) Fruit Extract). This is composed of natural biopeptides purified to 95%. These are obtained by up-cycling cranberry fruit press cake, a by-product of cranberry juice production.

The company said that it “prioritised a supplier committed to practices of sustainable development and implemented internally a specific eco-extraction process to produce the natural biopeptides”. Peptilium is now available as an 0.5-2% aqueous solution, has contents of 99% natural origin and is compliant with regulations in the EU, the USA, China and Japan.

The natural biopeptides in Peptilium can act transversally on several biological targets and on multiple skin parts. Thus, it is claimed to reinforce the epidermal barrier function and boost complexion radiance, as well as acting against wrinkles by improving the quality of the dermal-epidermal junction and the dermal matrix.

Silab carried out a targeted transcriptomic analysis on a Silabskin RE reconstructed epidermis that showed Peptilium, at 0.5%, restored keratinocyte proliferation and differentiation. It was also tested at 0.1% on aged fibroblasts and shown to increase the production of the collagen I network by 54%, thus keeping matrix fibres functionally organised.

Further tests over 21 days at 2% in an emulsion improved the parameters characteristic of complexion radiance in both Caucasian (reflection: +12%; pink colour: +17%) and Asian subjects (luminosity: +6%; olive colour: -5%). Similarly, it showed an anti-wrinkle effect in Caucasians (negative volume: -22%) and Asians (stage of crow’s feet wrinkles: -10%), the company stated.

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