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Retinyl esters are not alike: an in vitro study

This study analyses the effects of retinol and several retinyl esters on human dermal fibroblast proliferation and production of hyaluronic acid.

Retinol is well-established in cosmetics as an anti-ageing ingredient. It is known to increase cell proliferation and production of extracellular matrix elements such as hyaluronic acid. Anti-ageing products containing retinol may therefore decrease the appearance of wrinkles and improve skin texture. Unfortunately, retinol also suffers from chemical instability and the potential to irritate skin. To circumvent these issues, several derivatives of retinol have been developed with improved stability while still retaining the anti-ageing effects. The derivatives contain unsaturated fatty acids, either purified linoleic acid or a blend derived from sunflower seed oil. A comparative in vitro study was conducted to compare the effect of different test materials on human dermal fibroblast proliferation and production of hyaluronic acid. The test materials included retinol and three different esters of retinol (Retinyl sunflowerseedate, Retinyl linoleate, and Retinyl palmitate).

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Upcoming Events

in-cosmetics Korea 2022

Hall C, Coex, Seoul, South Korea
13 - 15 July 2022

PCHi China 2022

Shanghai World Expo Exhibition & Convention Center
18 - 20 July 2022

32nd IFSCC Congress

Park Plaza Hotel, Westminster
19-22 September 2022

in-cosmetics Asia 2022

BITEC Bangkok, Thailand
1 - 3 November 2022

SCS Formulate 2022

Coventry Building Society Arena
15 - 16 November 2022

8th Anti-Ageing Skin Care Conference

Royal College of Physicians, London
29 - 30 November 2022

Access the latest issue of Personal Care Magazine on your mobile device together with an archive of back issues.

Download the FREE Personal Care Magazine app from your device's App store

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