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Scalable active is able to mimic botox

Givaudan Active Beauty presents Zanthalene, a scalable natural active ingredient crafted by green fractionation with botox-like efficacy and skin sensitivity modulation benefits.

 Created from Zanthoxylum bungeanum, commonly known as Sichuan pepper, Zanthalene is a cosmetic ingredient derived from spice and able to act on neuromuscular communication within the skin structure, providing well-ageing effects and soothing benefits depending on its concentration in formulas. All consumers eventually experience the effects of ageing on the skin, such as wrinkles and sensitivity. However, a large number will not be motivated to reverse these effects through invasive treatments.

According to Givaudan's CMI study, 86% of consumers are currently interested in beauty products containing natural ingredients that help soothe skin discomfort while smoothing for a botox-like effect.

Giada Maramaldi, Personal Care Category Manager, Givaudan said: "Each facial expression activates a large number of muscles. With time and the decrease of collagen production, these expressions become even more marked and embedded on the skin, leading to the formation of wrinkles. In order to fight against these effects, Zanthalene offers a neurocosmetic strategy, enabling facial muscle relaxation in a safe, reversible and natural way, adding a sensation of comfort while removing skin discomfort."

Crafted from Sichuan pepper, a plant widely used as a spice in Asian cuisine, Zanthalene is extracted from its fruit husks using super critical CO2. Its efficacy has been proven during several clinical studies:

  • At low dosage (0.5%), Zanthalene is able to reduce skin discomfort such as itching and sensitivity by bringing a soothing effect to the skin in only a few minutes.
  • At higher dosage (1%), Zanthalene®shows a visible and immediate reduction of the skin's roughness parameter in only 30 minutes, and long-term efficacy over 30 days. This indicates that our organism continues to respond even over regular use of the product, creating a virtuous circle of amelioration.

Zanthalene is thus a perfect ingredient for formulation in beauty products targeting tired skin, aiming for a refreshed look and an immediately visible effect.

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Upcoming Events

The Society of Cosmetic Scientists, Singapore - 11th SCSS Suppliers Day, August 2021

Marriott Singapore, Tang Plaza Hotel. 320 Orchard Road
Thursday 26th & Friday 27th August 2021

in-cosmetics Global 2021 - Barcelona

Fira Barcelona
5 - 7 October 2021

in-cosmetics Asia 2021

BITEC Bangkok, Thailand
2 - 4 November 2021

NYSCC Suppliers’ Day 2021

Jacob K. Javits Convention Center, New York
10 - 11 November 2021

Access the latest issue of Personal Care Magazine on your mobile device together with an archive of back issues.

Download the FREE Personal Care Magazine app from your device's App store

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