In a current in vivo study, Symrise has found further proof that Crinipan PMC green (propanediol caprylate) – its novel, plant-based anti-dandruff active ingredient – performs equal to conventional systems.
The application of the ingredient compared to piroctone olamine on two groups of test subjects with dandruff resulted in a significant reduction of flaking with no difference between the two groups. A shampoo study at an external institute has yielded this result. It evaluated the degree of dandruff before and after a 28-day application of test shampoo on greasy scalp.
Previously, Symrise had already reported that Crinipan PMC green can reduce dandruff significantly versus placebo and works as effectively as the established active ingredient climbazole. Current data from a shampoo study carried out at an external institute further emphasises the effectiveness of the new product. As part of the test, dermatologists compared Crinipan PMC green to the established antidandruff active ingredient piroctone olamine and applied identical shampoo formulas containing either one on two groups of people with greasy scalp. Both test shampoos reduced dandruff significantly compared to the base values during a 28-day study. Crinipan PMC green stands out with a very innovative micro-activated mode of action to target dandruff.
The yeast Malassezia, known as one of the main causes for dandruff on scalp, activates the ingredient with its enzymes. Symrise has already demonstrated the effectiveness of Crinipan PMC green in several in vivo studies before. Next to its ability to reduce flaking on scalp, Crinipan PMC green has also been shown to support a healthy scalp microbiome and could improve sensorial parameters for the hair fibre, thus increasing the acceptance of hair and scalp care cosmetics by consumers.
