Recent studies for hair growth are being conducted on dermal papilla since it is important for developing follicles and there have been several pathways that have been identified such as the Wnt signalling pathway. RSPO1 is one of the recent novel proteins required for organ development, and is secreted from dermal papilla cells in the hair follicle. It has two functions - a promoter role and a protector role in the hair cycle. Nasturtium officinale Leaf/Stem Extract, a novel hair growth ingredient increases RSPO1 secretion from the derma papilla, and binds to the outer root sheath to promote hair follicle growth, and also neutralises the hair loss factor Dickkopf-related protein 1 (DKK1) to protect hair growth. The result of in vitro, ex vivo, and human clinical trial confirmed the efficacy of the special processed Nasturtium officinale Leaf/Stem Extract (commercially known as ‘Burgeon-Up’) to effectively promote hair growth through RSPO1 enhancement.
Hair los
