RSPO1 is one of the recent novel proteins required for organ development, and is secreted from dermal papilla cells in the hair follicle. It has two functions - a promoter role and a protector role in the hair cycle. Nasturtium officinale Leaf/Stem Extract, a novel hair growth ingredient increases RSPO1 secretion from the derma papilla, and binds to the outer root sheath to promote hair follicle growth, and also neutralises the hair loss factor Dickkopf-related protein 1 (DKK1) to protect hair growth. The result of in vitro, ex vivo, and human clinical trial confirmed the efficacy of the special processed Nasturtium officinaleLeaf/Stem Extract (commercially known as ‘Burgeon-Up’) to effectively promote hair growth through RSPO1 enhancement.
Hair loss is an issue that relates to both men and women of all ages and most of the time it imposes social and psychological difficulties.1 Current treatments like finasteride, minoxidil, and other drugs have unpredictable