A person’s perceived age is determined by physical traits on face and neck. These traits mostly reflect the integrity of the extracellular matrix, which provides structure, homogeneity and elasticity to skin.
Matrikines are dermal messenger peptides that instruct skin cells to reorganize and build up the extracellular matrix. So far, synthetic matrikines have been used in cosmetics. Now, for the first time, Lipoid-Kosmetik AG investigated and isolated natural matrikines-like peptides from cedar nuts and presents them in a novel anti-aging concentrate: PhytoCodine®.
Here we show that plant-derived, matrikine-like peptides mimic the activity of matrikines that naturally occur in our skin. Plant-derived, matrikine-like peptides activate the formation of extracellular matrix components, optimize skin structure, and improve age-related properties of mature skin, such as elasticity, density, wrinkles and sagging.
Altogether, PhytoCodine®is the first concentrate of plant-derived, natural matrikine-like peptides. It reprograms fibroblasts to build up extracellular matrix components characteristic of younger looking skin and thereby directly contributes to a person’s perceived age.
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