Ageing is one of the unavoidable processes in life and can be defined as changes in structures and tissue processes that affect related organs and systems with time.
We know that the environment and our relation with it can accelerate or delay cell ageing. Epigenetics helps us to understand how some genes involved in cell senescence, protection mechanisms and cell detoxication, and even the genes that participate in stem cell renovation, are regulated by processes based on DNA methylation, post-translational histone modifications and non coding RNAs (microRNAs and lncRNAs). Several studies have confirmed that cell ageing can be delayed, and even reversed, by epigenetic reprogramming. Evidently this discipline opens up endless possibilities for designing new anti-ageing strategies
The present article explains some ageing-related epigenetic mechanisms and how these mechanisms are a key element to consider in skin care and health. Finally, the potential that this discipline has on the generation and characterisation of new anti-ageing cosmetic active principles is described
The idea some years back of us being what our genes have written is changing because we now know that further regulations exist through the chemical modifications that take place in our DNA and in the proteins that package them, and that it is possible to regulate the expression of numerous genes.
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