Sustainable technology for natural efficacy

As precious sources of biologically active substances, plants have been widely cultivated both in open field and greenhouses with large amounts of natural resources and solvents for their extraction and purification.

However, water is a source of life and land is habitat for humans and animals, providing purified green spaces and soil for food cultivation. With growing global concern about the scarcity of these natural resources, it is fundamental to rationalise their use in a way that ensures their continued availability to sustain life for the future.

Using advanced biotechnologies, IRB has optimised an industrial cell culture method, called HTN (High Tech Nature) to produce plant active ingredients in safety and eco-sustainability conditions.


It may be a leaf, a flower or a seed. Only a small amount of plant tissue is required to find specific active substances. This small amount, however, requires in-depth scientific and technological knowledge to isolate and produce at highly scale molecules of interest.

This process shortens the distance to the ideal profile of the active plant ingredient, guaranteeing excellent quality standards, exceeding the limit of the traditional active ingredients:
Free from any type of pollutant, since plant stem cells are grown in a sterile and protected environment, without pesticides, heavy, metals and aflatoxines
Non GMO, as the DNA of plant cells remains intact 
With guaranteed high titre, thanks to ongoing selection of cells that produce more of the active ingredient 
Unlimited availability, using a biotech process that fully respects the environment and biodiversity
Totally eco-sustainable

Since the acquisition of IRB by Croda in July 2012, IRB’s exclusive know-how is combined with Sederma’s expertise in efficacy testing and proven ingredient functionality to offer a wide range of plant stem cell ingredients with guaranteed efficacy, reproducibility and measured sustainability:

Click on product name to request sample and/or literature.

Photo ageing protection: BUDDLEJA STEMS GX™
Titrated in phenylpropanoids expressed as verbascoside > 0.2%

Dark circles reduction: ECHINACELL™
China approved

Fights against rosacea: CENTECELL™
China approved

Collagen restructuring: GARDECELL™
China approved

Anti-pollution shield: MARRUCELL™
China approved

Wrinkle filler: LEONTOCELL™
China approved
Titrated in phenylpropanoids expressed as leontopodic acid > 0.1%

Reduction of acne signs and sebum control: SEBULESS™ (powder)
Titrated at 10% in phenylpropanoids expressed as verbascoside.



Upcoming Events

The Society of Cosmetic Scientists, Singapore - 11th SCSS Suppliers Day, August 2021

Marriott Singapore, Tang Plaza Hotel. 320 Orchard Road
Thursday 26th & Friday 27th August 2021

PCHi - Shenzhen 2021

Shenzhen Exhibition & Convention Center
24 - 26 March 2021

NYSCC Suppliers’ Day 2021

Jacob K. Javits Convention Center, New York
4 -5 May 2021

Cosmetic Ingredients & Technology Exhibition Japan (CITE JAPAN)

Pacifico Yokohama Exhibition Hall / North / Annex Hall
19 May – 21 May 2021

in-cosmetics Asia 2021

BITEC Bangkok, Thailand
2 - 4 November 2020

Upcoming Events

The Society of Cosmetic Scientists, Singapore - 11th SCSS Suppliers Day, August 2021

Marriott Singapore, Tang Plaza Hotel. 320 Orchard Road
Thursday 26th & Friday 27th August 2021

PCHi - Shenzhen 2021

Shenzhen Exhibition & Convention Center
24 - 26 March 2021

NYSCC Suppliers’ Day 2021

Jacob K. Javits Convention Center, New York
4 -5 May 2021

Cosmetic Ingredients & Technology Exhibition Japan (CITE JAPAN)

Pacifico Yokohama Exhibition Hall / North / Annex Hall
19 May – 21 May 2021

in-cosmetics Asia 2021

BITEC Bangkok, Thailand
2 - 4 November 2020