Sequential Skin Ltd
London
W1W 7LT
United Kingdom
(+44) 7832 237937
COMPANY INFORMATION
Headquarters
Sequential UK Lab
Sequential Skin Ltd c/o
Module 6 Phase B
Scale Space White City
Sequential Singapore Lab
Att. Dr Albert Dashi (+65 8750 2718)
Astar Central
79 Ayer Rajah Crescent, #05-03 Block 79, Singapore 139955
Sequential US Lab
Att. Sibora Peca (+1 (718) 902-6228)
JLABS/Sequential Skin Ltd
Sequential is the industry leader in microbiome testing, claims substantiation and support for brands formulating products for skin, scalp, intimate care and oral care. Recognized as the most significant testing solution in the industry, Sequential offers a full end-to-end platform from study design, recruitment and testing, to analysis, and support on formulation development and certification. Sequential’s testing is exclusively managed in-house and with human clinical subjects, in vivo. As an ally in research and development to top global brands and household names, Sequential supports their journey to delivering consumer driven products backed in science.
For more information, contact us at www.sequential.bio | team@sequential.bio
PRODUCTS AND SERVICES
Claims Testing: Certified to Maintain the Microbiome™
Sequential Bio has developed the gold standard test for products designed to target the microbiome, in vivo (in, or on, humans). Finally, we can give some certainty about if a product is truly having an affect on the microbiome.
Using next-generation sequencing of the collection of microorganisms found on the body, before and after product usage, Sequential Bio investigates the microbial diversity, and particular microorganisms we know are important and play a role in a healthy microbiome.
We give you an in vivo certification that your product is maintaining the microbiome. And it’s not exclusive to skincare! We do this for haircare products, oral care, and intimate care.
Longitudinal in vivo Study Design
Our study designs are centered around an in vivo approach (on human skin) acknowledging that the only way to test how a product is through real-life applications.
Clinical In-Vivo vs. In-Vitro
Longitudinal in vivo studies are not just a bonus for cosmetic and personal care brands to have within their repertoire. It is crucial to acknowledge that uncovering the real impact of products within the real context of the human body is the only way to understand how a product is functioning.
Why is it necessary to test the microbiome in vivo?
At present, there are no regulations for microbiome-related formulas that brands and formulators can follow, however, it has been universally acknowledged that the in vivo method of conducting clinical studies is becoming critical and paramount to getting marketing claims through. When regulations are introduced, which may be imminent, the in vitro system will find itself lacking, resulting in limited claims and certifications that do not hold their value. This is why, we at Sequential strive to offer an in vivo approach, knowing full well that we want our client's claims to be significantly backed by scientific and quantifiable data.
Longitudinal Design
Fit for clinical studies: one key benefit of in vivo testing is that we can design a study around the extended use of a personal care product with multiple timepoints. This allows us to review how a product is performing before and after usage, but also take into account its gradual impact on the microbiome.
Candidate Recruitment
We offer full candidate recruitment services for your desired studies removing the need for third-party (CRO) involvement in the study. If you are formulating for a specific type of concern, we can help recruit candidates that fit your criteria. We also offer recruitment of individuals of varying backgrounds if you have an interest in seeing how certain products interact with different ethnicities. The nature of our recruitment process is often linked to at-home testing, however, if you would prefer a controlled environment to test participants, we can arrange for testing to be conducted within our labs in Singapore, London and New York City.
Clinically Validated Collection System
Our user-friendly Sequential patch collection system consistently collects more material for downstream analysis and allows for remote testing. At Sequential, we have developed a proprietary patch to extract microbial material from the skin in a way that is more efficient than any other method within the industry.
Sequencing Technology
We offer four types of sequencing techniques including qPCR with Sequential Smart Probes™ on 20 key skin bacteria, 16S, ITS and Shotgun Metagenomics. Using next-generation sequencing of the collection of microorganisms found on the body, during product usage, Sequential investigates the microbial diversity, and particular microorganisms we know are important and play a role in a healthy microbiome.
In-house Analysis
All of our analysis is carried out in-house allowing for a faster turn-around time on your study as well as exclusive access to our team of scientists and formulation experts.
Claims Certification
We provide our clients with a certification to claim “Maintains the Microbiome” subject to in vivo testing results which can be used in communication efforts. Once your product is tested and has shown favorable results in supporting the microbiome, we can certify your product with our Maintains the Microbiome certification. We have ensured that our seal and certification are backed by quantifiable data and scientifically significant markers. The aim is to ensure our clients feel confident in making their claims and can communicate the true benefit of their microbiome formulations.
Testing Services
At Sequential, we have carried out extensive research on the microbiome, having captured over 16,000 microbiome samples. We pride ourselves in being the testing partner you need, with all the expertise and industry knowledge to support your formulation in its success. Whether you have developed a product for skin care, scalp care, intimate care or oral care we have the expertise and capabilities to test it for you.
Skin Care
By analyzing the unique composition of an individual's microbiome, skincare companies can tailor their products to promote a balanced and harmonious microbial community. Understanding the specific bacterial diversity and its interaction with the skin can allow for the formulation of personalized solutions that target specific concerns, such as acne, eczema, dehydration, etc.
Hair Care
Understanding the scalp microbiome allows formulators to address concerns such as dandruff, itchiness, or excessive oiliness and prevent scalp inflammation or infections. Testing scalp care products ensures that they are not only effective in addressing individual concerns but also gentle and supportive of the natural microbial community.
Oral Care
Testing the oral microbiome is crucial for oral care products. It ensures effective products that address concerns like tooth decay and gum disease while supporting a healthy oral microbiome. Microbiome testing enables the development of personalized solutions and promotes a balanced oral ecosystem.
Intimate Care
By conducting microbiome testing on intimate care formulations, manufacturers can address common concerns like yeast infections, bacterial vaginosis, or dryness. Microbiome testing in vaginal care products ensures that they are not only effective in addressing individual concerns but also gentle and supportive of the natural microbial community.
Looking to Create Your Next Best-Selling Formulation?
When it comes to understanding what makes a strong microbiome product, we are the experts. Having collected over 16,000 human skin microbiome samples through in vivo clinical research, we can help you take your product from conception to completion.
team@sequential.bio