Sederma has announced a new concept for skin moisturisation which is claimed to be based on cosmetogenomic progress. Revidrate is the first moisturiser that regulates the genes enabling the skin to recreate its own natural moisture.
The results from a DNA array study, in vitro and in vivo tests have shown its efficacy, confirming that the product enhances epidermis moisturisation and helps reinforce the cutaneous barrier by significantly increasing the production of NMF by 34.8% and the glycerol synthesis by 327%. The new moisturiser stimulates two enzymes involved in the filaggrine metabolism to synthesise the Natural Moisturising Factor (NMF). Moreover, the neosynthesis of intracellular glycerol has been confirmed. It reinforces the corneocyte envelope (synthesis of involucrin, transglutaminase and tight junctions), and the intercellular cement by lipid production (ceramides and cholesterol) ensuring the skin barrier function. Based on a complex lipid that mimics the effects of sphingosine-1 phosphate (S1P), which is a natural bioactive phospholipid known for its function on the epidermis maturation and filaggrinase stimulation, Revidrate stimulates all strategic molecules in and outside the cell for better moisture and improvement of the barrier.
