Winning time in fight against wrinkles

For the first time, the ageing genetic print has been defined and the “youth capital” code of the cells decoded. Three years of research led Seppic to identify the two active ingredients selected from among more than a hundred molecules. Their lipoaminoacid structure, obtained by biovectorisation of an amino acid on a lipid chain, optimises cutaneous bioaffinity for enhanced efficacy. Specially developed objectification protocols have demonstrated their performance against new causes of ageing (such as “inflamm-ageing”, reduction in stem cells longevity and cellular communication). Thanks to an original cell ageing model the genetic mapping of young and artificially-aged fibroblasts has been determined. Age-related expression of key genes has been decrypted. This genetic mapping protocol has enable the selection of the two active ingredients, TimeCode and SurviCode, that give cells a younger phenotype once more. (Fig.1). As skin ages, it is subjected to numerous stresses. The previously described protocol demonstrated that several genes are involved in skin ageing. It results in several physiological changes to the dermis and epidermis (listed in Fig. 2). The skin is sensitised, dull and less firm. TimeCode combats these skin changes. SurviCode prevents a loss of regeneration potential, cell anarchy and skin fragility. They fight against ageing via original and complementary mechanisms of action, in order to restore the skin’s youthfulness.

Fighting chronic ageing

TimeCode, referred to in this article as the first active, combats chronic ageing or “inflamm-ageing”, which sensitises the skin (inflammation code). It restores the skin’s microcirculation and provides the complexion with a new radiance (microcirculation code), and it strengthens the structure of the dermis, for a firmer skin (architecture code).