CLR reveals skin-brain benefit from cherimoya active ingredient

CLR has revealed test results for its AnnonaSense CLR (INI: Annona Cherimola Fruit Extract) active ingredient, which it says shows a perceivable improvement in sleep quality and skin appearance while reducing stress.

The German maker claims the study shows it is first cosmetic active ingredient with real clinical proof for positively influencing the entire skin-brain feedback loop.

To assess whether AnnonaSense CLR can really make a difference for the consumer, a new study was conducted by CLR on a total of 117 volunteers with sensitive skin and/or a stressful life (e.g. healthcare workers).

Part of the volunteers applied a cream containing the active ingredient; another part of the volunteers applied the same formulation with a placebo; and a third part applied the placebo and combined this with a facial massage which was expected to have a large impact on skin and wellbeing.

“The study clearly showed that AnnonaSense CLR has a strong influence on the entire skin-brain feedback loop. It perceivably improves the look and comfort of skin and it reduces psychological stress and improves quality of sleep,” said a CLR spokeswoman.

“Importantly, AnnonaSense CLR reduces the production of cortisol inside the body and, lastly and making this loop complete, it acts against the negative effects of systemic cortisol of skin by improving skin health,” she added.

The natural and upcycled active ingredient is obtained from Annona cherimola, common name cherimoya, an edible fruit originating from South America.     

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