Lubrizol Life Science Beauty has revealed the results of in vivo efficacy testing of its Actizyme advanced botanical ingredient.
Actizyme is a botanical extract rich in an acid protease that mimics the effect of endogenous cathepsin D to produce a controlled and effective desquamation, without side effects.
In desquamation, the skin cells go through a complete life cycle – from the base layer of the epidermis to the skin cells maturing and eventually flaking off at the surface.
When this process does not happen fully, dead skin cells can remain on the skin, making the skin look rough and dull.
In vivo efficacy testing of Actizyme was conducted on volunteers with darker complexions. Participants reported visible lightening effects and that their skin appeared more luminous.
It was demonstrated that when used in skin care formulations, Actizyme mimics the skin’s own desquamating enzymes.
“Previous studies have shown that Actizyme advanced botanical ingredient is a mild exfoliating ingredient that confers gentle cell turnover, compared to AHAs,” said Lubizol spokeswoman.
“For the first time, we have identified, in vitro, that the activity of the ingredient is highly specific to the conditions of the surface of the skin and its activity can be modulated by dosage and time to give a range of exfoliating effects,” she added.