Expo’biota: identifying impacts and solutions

Seqens reveals the details of a clinical study that demonstrates the beneficial properties of a plant extract derived from buckwheat seeds (Polygonum Fagopyrum syn. Polygonum fagopyrum) versus placebo when applied to skin naturally exposed to a polluted environment


A study of the characterization of bacterial populations in aerosols of polluted environments was carried out by high-throughput sequencing (16S rRN2 A) combined with bioinformatics analyses.

After highlighting some differences in the composition of the air and skin microbiota according to the level of pollution, we were able to show significant effects of a topical treatment versus placebo on specific skin parameters. This involved the development of a plant extract derived from buckwheat seeds (Polygonum Fagopyrum syn. Polygonum fagopyrum) applied topically in vivo to identify its effects on these parameters. We demonstrated the properties of this buckwheat extract applied to a panel of Parisian women naturally subjected to a polluted environment during one month of exposure. Significant evolutions were demonstrated both in terms of biometric and biological characteristics (skin tone, oxidation of stratum corneum proteins) associated with an impact on the cutaneous microbiota.

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