Noni active for skin microbiota rejuvenation

Spanish active ingredient producer Vytrus Biotech extols the benefits of its ingredient made from stem cells of noni, a traditional Polynesian plant. The ingredient is said to have a unique composition: a mixture of terpenes, polyphenols and phytosterols capable of rejuvenating the cutaneous microbiota and the skin at the same time

Traditionally, the hallmarks of ageing included a variety of aspects from the telomere shortening, the oxidative stress and the cellular senescence until epigenetics, among others.1 Nowadays, we know that the skin microbiota plays a key role in cutaneous homeostasis, and the skin microbial ecosystem evolves with age.2,3,4

The skin microbiota also ages. The cutaneous microbiota evolves as we age, so the skin microbial profiles can predict our age with a margin error precision of four years (Figure 1).5

Thus, the skin microbiota ages, and the characteristic trait of this process is that its behaviour changes to virulence.6,7 This change with its relationship with the host affects the ageing, including the skin. The resulting microbial postbiotic is rich in senile biome markers (SBMs)

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