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The anti-ageing effects of 2-aza-8-oxohypoxanthine

Vitamin C60 BioResearch Corporation has developed the world’s first cosmetic ingredient containing 2-aza-8-oxohypoxanthine (AOH), under the trade name Repista. This article describes the cellular activation effects of the AOH active ingredient on normal human epidermal keratinocytes

ABSTRACT

Vitamin C60 BioResearch Corporation has developed the world’s first cosmetic ingredient containing 2-aza-8- oxohypoxanthine (AOH), under the trade name Repista. This article describes the cellular activation effects of the AOH active ingredient on normal human epidermal keratinocytes. DNA microarray analysis using NHEKs suggested the AOH active ingredient promotes epidermal turnover, differentiation, and maturation, as well as the metabolism of old skin cells. In addition, all tests in the safety evaluation conducted on the AOH active ingredient were negative, indicating that it is a safe cosmetic ingredient. 

2-aza-8-oxohypoxanthine (AOH; Figure 1), is a plant growth factor discovered by Honorary Distinguished Professor of Shizuoka University Dr. Kawagishi.1 Until this discovery, there were only seven plant growth hormones recognized worldwide, making AOH the eighth plant growth hormone to be discovered. We expect the structure of AOH will be recognized as a major discovery and become textbook knowledge

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Upcoming Events

in-cosmetics Korea 2023

Hall C, Coex, Seoul, South Korea
12 - 14 July 2023

IFSCC 2023

Barcelona International Convention Centre
4 - 7 September

in-cosmetics Latin America 2023

Expo Center Norte, Sao Paulo
27 - 28 September

Cosmetorium 2023

Palau de Congressos de Barcelona
18 - 19 October

SEPAWA 2023

Estrel Congress Center, Berlin
25 - 27 October

California Chapter Suppliers’ Day 2023

Long Beach Convention Center
25 - 26 October

Access the latest issue of Personal Care Magazine on your mobile device together with an archive of back issues.

Download the FREE Personal Care Magazine app from your device's App store

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