Protecting keratinocytes stem cells from UVA harm

Gattefossé presents Solastemis, a sun care active ingredient that acts at the heart of the epidermis mechanics by protecting the DNA of keratinocytes from lesions induced by UVA radiation and by boosting endogenous DNA repair capacity

ABSTRACT

Eco-designed and sustainably sourced active ingredient, Solastemis™ acts at the heart of the epidermis mechanics by protecting the DNA of keratinocytes from lesions induced by UVA radiation and by boosting endogenous DNA repair capacity. Doing so, it preserves the stem cells of the epidermis, thus ensuring proper homeostasis for the skin’s first line of defence. Beyond epidermis, it also offers a shield for the extra-cellular matrix by protecting key proteins (collagen, elastin) from degradation induced by solar exposure. Photoageing-associated symptoms are visibly corrected versus placebo: wrinkles and skin microrelief are significantly improved. The skin complexion appears brighter, more even and healthier. 

As humans are faced with more extreme conditions due to climate change, the need for skin protection has become predominant in the beauty sector. The status of the skin itself is changing: it is considered as an organ in interaction with its surroundings and ever more challenging environment. 

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