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Inolex expands novel alkylhydroxamic acid patent portfolio

Inolex has expanded its existing global patent portfolio of novel alkylhydroxamic acid technology with the issuance of several new patents directed to the use of caprylhydroxamic acid and related alkylhydroxamic acids for preservation of cosmetic, beauty, and personal care formulations.

Caprylhydroxamic acid (CHA) is a 100% natural and readily biodegradable chelating agent that efficiently binds iron ions, resulting in a strong fungistatic effect. Additionally, its C8 acyl carbon chain imparts bacteriostatic character.

The combination of these properties provides strong preservation effects in formulations by creating an environment that inhibits microbial growth.

Combinations of CHA with medium chain terminal diols (MCTDs) are ideal for microbial control in cosmetic formulations, as demonstrated through Inolex’s portfolio of safe, broad spectrum preservation solutions.

The newly issued US Patent US11291204B2 is titled “Preservatives for cosmetic, toiletry and pharmaceutical compositions” and covers preservation compositions having a C6, C8, C10, or C12 alkylhydroxamic acid, including CHA, in combination with a variety of medium chain terminal diols such as caprylyl glycol; glyceryl caprylate; and caprylyl glyceryl ether.

Inolex products covered by this patent are offered under the Spectrastat brand, and include Spectrastat, Spectrastat G2 Natural MB, Spectrastat CGE Natural MB, and Spectrastat MHG Natural MB.

In addition to the aforementioned patent, the company has expanded the global reach of its alkylhydroxamic acid portfolio with Chinese Patent CN107595662B, titled “Synergistic compositions, formulations and related methods for reducing ultraviolet-induced lipid peroxidation”, and covers synergistic compositions of alkylhydroxyamic acids, including CHA, with antioxidants to reduce ultraviolet-induced lipid peroxidation.

The patent also claims alkylhydroxamic acids in combination with antioxidants including ascorbic acid; sodium ascorbyl phosphate; ascorbyl palmitate; tocopherols (vitamin E); tocopheryl acetate (vitamin E acetate); butylated hydroxytoluene; butylated hydroxyanisole; resveratrol; quercetin; uric acid; carotenes; glutathione; melatonin and mixtures thereof.

An additional patent application in Europe for the use of combinations of alkyl ethers of glycerol and CHA in cosmetic and dermatological formulations is pending.

This application compliments an existing portfolio of patents in Europe, acquired by Inolex, that cover the use of CHA in applications including hair styling with flexible hold, dandruff control in combination with sorbic acid, and combinations of CHA with aromatic alcohols.

Inolex ingredients covered by the latter include Phenostat, Benzostat, and Aromastat.

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Upcoming Events

in-cosmetics Global

Paris Expo Porte de Versailles
16th – 18th April 2024

NYSCC Suppliers' Day 2024

Javits Center, New York
1st - 2nd May 2024

9th Anti-Ageing Skin Care Conference

Royal College of Physicians, London
25th - 26th June 2024

in-cosmetics Korea 2024

Hall C, Coex, Seoul, South Korea
24th - 26th July 2024

in-cosmetics Latin America 2024

São Paulo, Brazil
25th - 26th September 2024

IFSCC 2024

Recanto das Cataratas Thermas Resort, Iguazu Falls, Brazil
14th - 17th October 2024

Access the latest issue of Personal Care Magazine on your mobile device together with an archive of back issues.

Download the FREE Personal Care Magazine app from your device's App store

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