Seppic has launched Subligana, an active ingredient for antiimperfection, anti-spot & flawless-looking complexion concepts related to oxidative stress, designed by Serdex, a subsidiary of Seppic. Acne affects 80% of people at some point in their lives. New studies have shown that an increased cutaneous and systemic oxidative stress is involved.
Subligana is a titrated extract of Harungana madagascariensis which originates in Madagascar. By forming a physical and a repulsive barrier, Harungana madagascariensis protects primary forest areas from attacks and is capable of restoring degraded landscapes.
It is considered by botanists as a ‘forest guard’. Traditionally, leaf decoctions are used against asthma and skin disorders and leaf juice is used for wound healing.
Subligana addresses blemished skins and acneprone skins. An in-use test on teenagers presenting acneprone skin showed a significant whitehead reduction versus placebo after 28 days. Subligana’s mechanism of action combines soothing effect (lipase inhibition, IL-10 and IL-12 regulation), antioxidant effect (protection against lipid peroxidation) and efficacy against Propionibacterium acnes.