Rapid anticholinergic effect on skin relaxation

The enzyme acetylcholinesterase is found to be present in the synapses between nerve cells and muscle cells. When a motor neuron receives signals from the brain and spinal cord, it releases acetylcholine and causes muscle contractions.

Acetylcholinesterase converts acetylcholine in an inactive product, choline. An increase of the enzyme activity in the presence of acetylcholine, leads to an increase in the amount of choline and muscle relaxation.

The evidenced enzymatic effect results in a relaxation of facial skin muscles, which means having smoother and less tense skin with a significant influence on skin roughness and ageing. In fact, when applied topically, the product can reduce the tonic contraction of the facial muscles responsible for the appearance of expression lines.

Methods

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