Nanoemulsions: preparation techniques and applications

Recently, there has been a great potential to use nanotechnology in cosmetic and pharmaceutical applications. In many cosmetic products including moisturisers, hair care products, make up and sunscreen one can find the traces of nanotechnology.1

Nanoemulsions are dispersions of small droplets, usually in the 10 nm-500 nm size range, one liquid within another.2,3 They are water-in-oil (W/O) or oil-in-water (O/W) form and transparent or translucent. Due to their small droplet size, the force of gravity can be reduced and no creaming, sedimentation and flocculation occur during storage. Also, their ability to improve the bioavailability and bioefficacy of lipophilic bioactives in delivery systems is another goal. Nanoemulsions are non-toxic and non-irritant, hence can be easily applied to skin and mucous membranes. They can be stabilised to increase the time before creaming occurs, therefore increasing the shelf life of products containing them. They can be formulated in a variety of formulations such as foams, creams, liquids and sprays. These advantages make nanoemulsions preferable.

Preparation techniques

Nanoemulsions can be prepared by high pressure homogenisation, microfluidisation and Phase Inversion Temperature method.

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