Vivimed Skin Lightening Formulation Formula Ref. 2-016-42

Vivimed Labs Ltd
Phase
Product
INCI Name
Supplier
Volume
A
Tego Care 450
Polyglyceryl-3 Methyglucose Distearate
Evonik
3.00
Span 60
Sorbitan Stearate
Croda
2.00
Lanette 18
Stearyl Alcohol
BASF
1.00
Tegosoft XC
Phenoxyethyl Caprylate
Evonik
5.00
Cetiol CC
Dicaprylyl Carbonate
Evonik
5.00
Crodamol AB
C12-15 Alkyl Benzoate
Croda
7.50
Euxyl PE9010
Phenoxyethanol (and) Ethylhexylglycerin
Schulke & Mayr
1.00
OMC
Ethyl Hexyl Methoxycinnamate
Various
4.00
RonaCare AP
Bis-ethylhexyl Hydroxydimethoxy Benzylmalonate
Merck
1.00
Avis
Butyl Methoxydibenzoylmethane
Vivimed
3.00
Etone
Ethylhexyl Triazone
Vivimed
2.00
Vivinol
4-butylresorcinol
Vivimed
0.10
Titriplex III
Disodium EDTA
Merck
0.10
Vitamin E Acetate
Tocopheryl Acetate
Various
1.00
B
Deionised Water
Aqua
59.20
Pricerine 9091
Glycerine
Croda
3.00
Carbopol Ultrez-10 (5% Solution)
Carbomer
Lubrizol
2.00
Keltrol CG-RD
Xanthan Gum
CP Kelco
0.10

Preparation:

1. Pre-mix glycerine and Keltrol. Add water with stirring. Add Carbopol with stirring. 2. Once dispersed heat to 75-80oC. 3. Combine oil phase ingredients (phase A) and heat to 75-80oC. 4. Add oil phase to water phase with stirring. 5. Homogenise for 2 minutes. 6. Cool with stirring to 35oC. Neutralise to pH7 with triethanolamine. 7. Continue colling with stirring to room temperature.

Notes:

Test Data: 49400cps / pH7 / in-vitro SPF16 / UVA:UVB ratio 0.733
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