Concept Of Eye Illumination (Gel) MDA-A-124-03

Merck KGaA
Phase
Product
INCI Name
Supplier
Volume
A
Water, demineralized
ad 100
RonaCare® Ectoin
ECTOIN
1
0.30
RonaCare® Troxerutin
TROXERUTIN
1
0.50
Caffeine
Caffeine
1
0.30
Titriplex® III
DISODIUM EDTA
1
0.10
Carbopol ETD 2050
CARBOMER
2
0.30
B
RonaCare® Triethanolamine
Triethanolamine
1
0.05
C
RonaCare® Cyclopeptide-5
AQUA (WATER), ALCOHOL DENAT., LECITHIN, ECTOIN, CYCLOTETRAPEPTIDE-24 AMINOCYCLOHEXANE CARBOXYLATE
1
3.00
D
RonaCare® Triethanolamine
TRIETHANOLAMINE
1
0.20
Preservatives
qs

Preparation:

Dissolve the ingredients of phase A into water and disperse the Carpopol in phase A.Preneutralize with phase B to pH ~5. Finally add phase C and adjust to pH5.5-6.0.

Notes:

Appearence: transparent yellow gelpH (23°C): 5.5-6.0Viscosity: 3500 mPa s (Brookfield RV II+, Helipath spindle B, 10 rpm) at 23°CStability: 3 month at 40°C, FTC(-5°C to 40°C), 5°C, RT and 1 week at 50°C Suppliers: (1) Merck KGaA, Darmstadt, Germany / EMD Chemicals (2) Lubrizol (3) Parfex (4) Schülke & Mayr GmbH
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